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Table 2 Pathways identified by functional enrichment analysis (GSE16558)

From: anamiR: integrated analysis of MicroRNA and gene expression profiling

Category

Function

Number of genes

Number of genes targeted by miRNAs

P-valuea

Empirical p-valueb

Reactome

Gene expression

1588

15

6.06E-07

0.0002

Reactome

Transcriptional regulation by TP53

345

7

6.90E-06

0.0002

KEGG

FoxO signaling pathway

126

4

0.0001

0.0002

BioCarta

p53 signaling pathway

13

2

0.0003

0.0004

BioCarta

Hypoxia and p53 in the cardiovascular system

21

2

0.0008

0.0005

  1. aThe P-value was obtained by the hypergeometric test
  2. bThe P-value was obtained by the permutation test
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BMC Bioinformatics

ISSN: 1471-2105

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