TY - JOUR AU - Chen, Jiao AU - Huang, Jiating AU - Sun, Yanni PY - 2019 DA - 2019/06/04 TI - TAR-VIR: a pipeline for TARgeted VIRal strain reconstruction from metagenomic data JO - BMC Bioinformatics SP - 305 VL - 20 IS - 1 AB - Strain-level RNA virus characterization is essential for developing prevention and treatment strategies. Viral metagenomic data, which can contain sequences of both known and novel viruses, provide new opportunities for characterizing RNA viruses. Although there are a number of pipelines for analyzing viruses in metagenomic data, they have different limitations. First, viruses that lack closely related reference genomes cannot be detected with high sensitivity. Second, strain-level analysis is usually missing. SN - 1471-2105 UR - https://doi.org/10.1186/s12859-019-2878-2 DO - 10.1186/s12859-019-2878-2 ID - Chen2019 ER -