Table 5 NSCLC case study. miRNAs and their targets selected for the proposed case study
From: MiRNA therapeutics based on logic circuits of biological pathways
miRNA | Target |
|---|---|
let-7c | CCND1, KRAS |
let-7g | AKT,CCND1 |
mir-130b | RASSF1,STAT3 |
mir-142 | CCND1,FOXO3, ERK |
mir-15a | AKT, CCND1 |
mir-17 | PKC, STAT3 |
mir-18a | CCND1,TGFA |
mir-191 | BRAF |
mir-193b | CCND1, PKC |
mir-27a | SOS |
mir-27b | PDK1 |
mir-29a | AKT,CDK4 |
mir-30e | KRAS,TGA |
mir-330 | BAD |
mir-335 | FOXO3,JAK3 |
mir-34a | CDK6,MEK |
mir-375 | PI3K,PKC |
mir-4778 | PKC, STAT/3 |
mir-4789 | CCND1, STAT5 |
mir-497 | CDK4, GRB2 |