Fig. 6
From: Time varying causal network reconstruction of a mouse cell cycle
MEF cell cycle network for G1 and S phases followed by the G2/M phases. The graph reconstruction of the network representing the causal interactions of 63 cell cycle genes obtained by using only the data samples in the interval {1–28.5} hour of the cell cycle associated with the G2/M phase. The blue edges represent true positive (TP) connections validated though the known literature (STRING database). The green edges represent true indirect affinities between the pairs of genes they are connected to, and the gray edges are interactions captured only in our model, serving as potential novel hypotheses. The node colors denote the optimal time lag corresponding to every target gene in the VAR model. See Additional file 5 for the complete list of interactions in the above network