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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Identification of critical connectors in the directed reaction-centric graphs of microbial metabolic networks

Fig. 3

Number distributions of total reactions and essential reactions according to each of the centrality measures in the reaction-centric network of E. coli. (a) bridging centrality, (b) betweenness centrality, (c) clustering coefficient, and (d) total degree. In each stacked bar, the numbers of predicted essential and non-essential reactions are colored in black and gray, respectively, and their summation is equal to the number of total reactions in E. coli. A reaction was considered essential if when its removal from the model led to a growth rate less than the default threshold of 5% of the growth objective value simulated for the wild type strain. The percentage of essential reactions among the total reactions is denoted as a black circle

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BMC Bioinformatics

ISSN: 1471-2105

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