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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Identifying lncRNA-mediated regulatory modules via ChIA-PET network analysis

Fig. 1

Overview of the hierarchical graph analysis. The different levels represent a zoom into more detail in the graph, starting with the chromatin graph at the top, then focusing on a single chromosome followed by large connected components and lastly modules detected in the large component using the MSM algorithm or as small connected components of the corresponding chromosome. On the right, we list the different analysis steps performed at each level, focusing only on degree centrality on the level of the chromatin graph, then adding in consideration of connectivity properties as well as module detection and finally considering molecular information to assess possible functional interactions within modules. Node shapes are arbitrary and node colors symbolize different node annotations

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