Table 6 AUCs of cross-species predictions of PPI-MetaGO/go2ppi-NB using the biological process (BP), cellular component (CC), and molecular function (MF) ontology, respectively

BP

Train

AUC

EC2

SP

HS4

SC2

DM2

AT

MM

EC2

0.94/0.88

0.92/0.78

0.86/0.76

0.87/0.77

0.69/0.80

0.73/0.64

0.59/0.65

SP

0.87/0.65

0.96/0.81

0.88/0.74

0.87/0.75

0.68/0.74

0.78/0.55

0.60/0.61

HS4

0.90/0.72

0.94/0.75

0.95/0.76

0.88/0.73

0.71/0.80

0.76/0.64

0.63/0.68

SC2

0.89/0.80

0.95/0.79

0.90/0.76

0.95/0.79

0.76/0.83

0.73/0.67

0.58/0.70

DM2

0.83/0.60

0.92/0.70

0.85/0.71

0.87/0.67

0.79/0.78

0.68/0.63

0.58/0.60

AT

0.82/0.72

0.91/0.80

0.84/0.74

0.86/0.75

0.73/0.76

0.86/0.72

0.61/0.63

MM

0.81/0.62

0.87/0.71

0.85/0.73

0.85/0.71

0.70/0.74

0.69/0.56

0.73/0.69

CC

Train

AUC

EC2

SP

HS4

SC2

DM2

AT

MM

EC2

0.94/0.88

0.91/0.67

0.86/0.68

0.87/0.68

0.68/0.74

0.71/0.59

0.55/0.66

SP

0.85/0.55

0.96/0.82

0.88/0.70

0.88/0.78

0.66/0.73

0.73/0.61

0.56/0.56

HS4

0.89/0.70

0.94/0.70

0.95/0.80

0.88/0.77

0.71/0.79

0.75/0.65

0.66/0.68

SC2

0.89/0.78

0.95/0.74

0.90/0.76

0.94/0.83

0.75/0.80

0.72/0.65

0.58/0.64

DM2

0.82/0.64

0.91/0.69

0.84/0.74

0.87/0.79

0.81/0.80

0.70/0.63

0.58/0.60

AT

0.79/0.57

0.90/0.66

0.84/0.67

0.85/0.73

0.67/0.70

0.85/0.71

0.61/0.61

MM

0.76/0.70

0.87/0.71

0.86/0.74

0.85/0.77

0.68/0.77

0.61/0.61

0.70/0.70

MF

Train

AUC

EC2

SP

HS4

SC2

DM2

AT

MM

EC2

0.94/0.88

0.92/0.65

0.87/0.62

0.87/0.66

0.69/0.70

0.74/0.62

0.57/0.56

SP

0.85/0.81

0.97/0.76

0.87/0.65

0.87/0.67

0.68/0.72

0.76/0.67

0.58/0.57

HS4

0.89/0.85

0.94/0.78

0.95/0.76

0.88/0.68

0.72/0.76

0.75/0.67

0.63/0.68

SC2

0.88/0.89

0.95/0.73

0.89/0.66

0.95/0.76

0.75/0.75

0.74/0.59

0.55/0.62

DM2

0.79/0.80

0.92/0.68

0.85/0.65

0.86/0.66

0.82/0.79

0.72/0.67

0.57/0.60

AT

0.75/0.72

0.93/0.70

0.83/0.63

0.83/0.60

0.72/0.70

0.86/0.75

0.61/0.58

MM

0.79/0.77

0.88/0.66

0.86/0.67

0.85/0.65

0.67/0.74

0.71/0.70

0.72/0.67