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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Stochastic modeling of aging cells reveals how damage accumulation, repair, and cell-division asymmetry affect clonal senescence and population fitness

Fig. 2

a Sensitivity analysis for the clonal senescence outcome. The parameter combinations tested were partitioned into groups such that all combinations in each group differs only in the value of one parameter. The fraction of groups with divergent senescence outcome is plotted for each parameter. b Sensitivity analysis for the doubling time outcome. The parameter combinations tested were partitioned into groups such that all combinations in each group differs only in the value of one parameter. The fraction of groups where the minimum doubling time is at least 5% below the maximum is plotted for each parameter. Level of transparency indicates the size of the effect. In each panel, the color indicates the value of the parameter corresponding to the most-fit combination in the group: red indicates that the smallest parameter value is the most fit; blue indicates that the largest parameter value is the most fit; and green indicates that an intermediate parameter value is the most fit

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BMC Bioinformatics

ISSN: 1471-2105

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