DDGun: an untrained method for the prediction of protein stability changes upon single and multiple point variations

Table 1 Pearson correlation between scores and ∆∆G

Data set	VariBench 1564 variants	Broom et al. 605 variants	S2648 2648 variants	P53 42 variants	Myoglobin 134 variants
Score	VariBench 1564 variants	Broom et al. 605 variants	S2648 2648 variants	P53 42 variants	Myoglobin 134 variants
s _Bl	0.269	0.354	0.284	0.636	0.148
s _Sk	0.398	0.423	0.387	0.328	0.454
s _Hp	0.248	0.263	0.298	0.143	0.500
s _BV	0.452	0.581	0.497	0.423	0.548

The Pearson correlation coefficient and the scores were calculated as described in the Method section. The composition of the data sets is summarized in the Data sets section

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