Table 3 List of species included in the EGFR-IGF1R model and the corresponding initial concentrations and total protein amount
State Variable | Species | Value |
|---|---|---|
x 1 | EGFR ∗ | 8000 |
x 2 | IGF1R ∗ | 650 |
x 3 | SOS | 0 |
x 4 | Ras ∗ | 0 |
x 5 | Raf ∗ | 0 |
x 6 | MEK ∗ | 0 |
x 7 | Erk ∗ | 0 |
x 8 | p90Rsk ∗ | 0 |
x 9 | PIK3 ∗ | 0 |
x 10 | Akt ∗ | 0 |
u 1 | RafPP | 120000 |
u 2 | PP2A | 120000 |
u 3 | RasGab | 120000 |
\(x_{3}^{T}\) | DSOS | 120000 |
\(x_{4}^{T}\) | Ras | 120000 |
\(x_{5}^{T}\) | Raf | 120000 |
\(x_{6}^{T}\) | MEK | 600000 |
\(x_{7}^{T}\) | Erk | 600000 |
\(x_{8}^{T}\) | p90Rsk | 120000 |
\(x_{9}^{T}\) | PIK3 | 120000 |
\(x_{10}^{T}\) | Akt | 120000 |