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Table 5 Computational cost to run the CRA algorithm in all the examples provided in the Results section

From: CRA toolbox: software package for conditional robustness analysis of cancer systems biology models in MATLAB

Model

Output node

Evaluation Function

Time (sec.)

  

Area

45

Pulse Generator Network

Y

Maximum

45

  

Time of Maximum

42

  

Area

1702

 

C2

Maximum

1703

Prostate-specific Pten−/− mouse model

 

Time of Maximum

1706

 

C1

Area

1708

EGFR-IGF1R pathway in lung cancer

ERK

Area

102

  1. The times are expressed in seconds and they refer to a single realization of the CRA