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Table 1 Overview of the evolutionary algorithm formulations used in this work. Both objective functions are represented, as well as other constraints that condition the acceptance of a given candidate as a valid solution

From: Comparison of pathway analysis and constraint-based methods for cell factory design

Formulation

Objective function #1

Objective function #2

Additional constraints

EAw

Z =  Max (vb)

Max(vp)

None

EAm

Max(W =  Min (vp))s. t. vb = Z

Accept solution if \( {v}_p>0\ if\ {v}_b>\frac{Z}{2} \)