Table 2 Overview of the constraints for the undesired space (T) used in formulations involving enumeration of constrained minimal cut sets
From: Comparison of pathway analysis and constraint-based methods for cell factory design
Formulation | Product constraint | Substrate constraint | Coupling constraint | Biomass constraint |
|---|---|---|---|---|
MCSe | \( \frac{v_p}{v_s}\le {y}_{min} \) | vs ≤ smax | vatp ≥ m | None |
MCSf | vs = smax | None | ||
MCSw | vp ≤ ε | vs = smax | None | vb ≥ F. bmax |