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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Prediction of regulatory targets of alternative isoforms of the epidermal growth factor receptor in a glioblastoma cell line

Fig. 5

Reduction of the conceptual gene groups. Genes of group A are never differentially expressed by EGF treatment. Genes of group B and E - G are always differentially expressed by EGF treatment. Genes of group C and H are differentially expressed by EGF treatment in case of control treatment (no RNAi) or simultaneous treatment with siRNAI, whereas not differentially expressed by EGF treatment in case of simultaneous treatment with siRNAALL. Genes of group D are differentially expressed by EGF treatment in case of control treatment (no RNAi), whereas not differentially expressed by EGF treatment in case of simultaneous treatment with siRNAI or siRNAALL. We find that the eight gene groups show only four different expression patterns, so we reduce the eight gene groups A - H to the four simplified gene groups a - d, where group A becomes group a, the union of the groups B and E - G becomes group b, the union of the groups C and H becomes group c, and group D becomes group d

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