Skip to main content

Table 2 Percentage of metabolites for which strain designs of type wGC, hGC or sGC were identified. Strain designs were computed by gcOpt with the E. coli iAF1260 core model and glucose as the sole carbon and energy source. The total number of investigated carbon metabolites was 36

From: Determination of growth-coupling strategies and their underlying principles

  Metabolites for which the best GC strategy was of type [%] Metabolites that could be coupled to growth [%]
wGC hGC sGC
Aerobic
 standard 6 6 78 89
 ATPM high 17 3 69 89
 ATPM low 6 11 72 89
 NADH demand 17 3 69 89
 NAD+ demand 17 11 61 89
 NADPH demand 33 6 50 89
 NADP+ demand 25 11 39 75
Anaerobic
 standard 14 3 19 36
 ATPM high 3 14 17 33
 ATPM low 0 3 53 56
 NADH demand 3 14 19 36
 NAD+ demand 3 6 31 39
 NADPH demand 3 14 25 42
 NADP+ demand 3 8 19 31