Determination of growth-coupling strategies and their underlying principles

BMC Bioinformatics

Table 2 Percentage of metabolites for which strain designs of type wGC, hGC or sGC were identified. Strain designs were computed by gcOpt with the E. coli iAF1260 core model and glucose as the sole carbon and energy source. The total number of investigated carbon metabolites was 36

	Metabolites for which the best GC strategy was of type [%]			Metabolites that could be coupled to growth [%]
	wGC	hGC	sGC	Metabolites that could be coupled to growth [%]
Aerobic
standard	6	6	78	89
ATPM high	17	3	69	89
ATPM low	6	11	72	89
NADH demand	17	3	69	89
NAD⁺ demand	17	11	61	89
NADPH demand	33	6	50	89
NADP⁺ demand	25	11	39	75
Anaerobic
standard	14	3	19	36
ATPM high	3	14	17	33
ATPM low	0	3	53	56
NADH demand	3	14	19	36
NAD⁺ demand	3	6	31	39
NADPH demand	3	14	25	42
NADP⁺ demand	3	8	19	31

ISSN: 1471-2105