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Fig. 22 | BMC Bioinformatics

Fig. 22

From: Visualization methods for differential expression analysis

Fig. 22

Standardized scatterplot matrix for gene cluster that remained as liver-specific DEGs after TMM normalization. Scatterplot matrix of the standardized 933 genes that were in the first cluster (Fig. 18) from genes that remained as liver-specific DEGs even after TMM normalization. Even though the standardization process removes the interesting geometrical features we would otherwise see, it amplifies DEG patterns in meaningful ways. Here, the highlighted genes appear more clustered and separated from the x=y line in the treatment scatterplots, and more clustered and connected to the x=y line in the replicate scatterplots. We can also now see more clearly in the replicate scatterplots that the liver expression is higher than the kidney expression

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