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Table 4 Top significant biological process GO term for each miRNA. ‘Count’ represents number of miRNA targets enriched

From: miRFA: an automated pipeline for microRNA functional analysis with correlation support from TCGA and TCPA expression data in pancreatic cancer

miRNA

GO term

Count

P-value

hsa-let-7d-3p

GO:0051962 positive regulation of nervous system development

5

0.001

hsa-miR-101-3p

GO:0019219 regulation of nucleobase-containing compound metabolic process

249

<  0.001

hsa-miR-106b-5p

GO:0007399 nervous system development

356

<  0.001

hsa-miR-130b-3p

GO:0046834 lipid phosphorylation

11

<  0.001

hsa-miR-144-3p

GO:0072659 protein localization to plasma membrane

7

0.001

hsa-miR-22-5p

GO:0051641 cellular localization

253

<  0.001

hsa-miR-24-3p

GO:0023051 regulation of signaling

516

<  0.001

hsa-miR-26a-5p

GO:0002009 morphogenesis of an epithelium

28

<  0.001

hsa-miR-34a-5p

GO:0050794 regulation of cellular process

1084

<  0.001

hsa-miR-423-3p

GO:0065009 regulation of molecular function

77

<  0.001

hsa-miR-451a

GO:0000165 MAPK cascade

8

<  0.001

hsa-miR-574-3p

GO:0071495 cellular response to endogenous stimulus

22

0.001

hsa-miR-885-5p

GO:0031323 regulation of cellular metabolic process

603

<  0.001

  1. NA not applicable