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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Analyzing magnetic bead QuantiGene® Plex 2.0 gene expression data in high throughput mode using QGprofiler

Fig. 5

PCA based compound ranking with superimposition of the gene signature. The first principal component is mainly driven by the disease genes. Compounds can be prioritized based on PCA weighed distances as illustrated for cpd_034 (rank 3) and cpd_065 (rank 18), with compounds on the left of the refCpd having some promising transcriptional signal for the target related gene signature

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