Table 1 Overview of the different experimental settings with number of samples, compounds, genes, HKG and background used to assess the ideal number of beads, linearity of HKG signal and overall QGprofiler data flow. Where samples are either vehicle or compounds tested in multiple dose in a particular background
Experiment | # Samples | Total # Genes | # HKG | # Compounds | Background | |
|---|---|---|---|---|---|---|
Bead Number | Dataset 1 | 46 | 14 | 3 | 2 | Xenograft A |
Dataset 2 | 6 | 14 | 3 | 1 | Xenograft B | |
Dataset 3 | 132 | 18 | 3 | 19 | Cell line C | |
Linearity of HKG | Dataset 4 | 60 | 26 | 26 | 0 | Cell line C |
Data Analysis Flow | Dataset 5a | 60 | 20 | 2 | 10 | Cell line C |