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Table 2 List of GO terms with significantly different changes in the functional sub-networks in H12

From: Analysis of networks of host proteins in the early time points following HIV transduction

GO code

GO term

Significantly changed parameter

Direction of change in H12

GO.0005759

mitochondrial matrix

Nf

decrease

GO.0003674

molecular function

Df, Dc

increase

GO.0003723

RNA binding

Rf, Rc

increase

GO.0005488

binding

Df, Dc

increase

GO.0005615

extracellular space

Rf, Rc

increase

GO.0005634

nucleus

Df, Dc

increase

GO.0005654

nucleoplasm

Df, Dc

increase

GO.0005739

mitochondrion

Df

increase

GO.0005743

mitochondrial inner membrane

Df, Dc

increase

GO.0005759

mitochondrial matrix

Df

increase

GO.0005856

cytoskeleton

Df, Dc

increase

GO.0006401

RNA catabolic process

Df, Dc

increase

GO.0006402

mRNA catabolic process

Df, Dc

increase

GO.0009058

biosynthetic process

Rf, Rc

decrease

GO.0009987

cellular process

Df, Dc

increase

GO.0010467

gene expression

Rf, Rc

increase

GO.0016032

viral process

Rf

increase

GO.0016604

nuclear body

Nf

decrease

GO.0017076

purine nucleotide binding

Df, Dc

increase

GO.0019058

viral life cycle

Df, Dc

increase

GO.0022607

cellular component assembly

Df

increase

GO.0030054

cell junction

Df

increase

GO.0031966

mitochondrial membrane

Df, Dc

increase

GO.0031981

nuclear lumen

Df, Dc

increase

GO.0043066

negative regulation of apoptotic process

Df

increase

GO.0043209

myelin sheath

Df

increase

GO.0043232

intracellular non-membrane-bounded organelle

Df

increase

GO.0043933

macromolecular complex subunit organization

Rf, Rc

increase

GO.0044237

cellular metabolic process

Df

increase

GO.0044265

mitochondrial nucleoid

Df, Dc

increase

GO.0044428

nuclear part

Df, Dc

increase

GO.0044430

cytoskeletal part

Df, Dc

increase

GO.0044451

nucleoplasm part

Nf

decrease

GO.0044712

single-organism catabolic process

Nf

decrease

GO.0044765

single-organism transport

Df, Dc

increase

GO.0044822

poly(A) RNA binding

Rf

increase

GO.0051084

de novo posttranslational protein folding

Rf, Rc

increase

GO.0051704

multi-organism process

Rf, Rc

increase

GO.0060548

negative regulation of cell death

Df

increase

GO.0071013

catalytic step 2 spliceosome

Df

increase

GO.0071705

nitrogen compound transport

Nf

decrease

GO.0071822

protein complex subunit organization

Rf

increase

GO.1901575

organic substance catabolic process

Df

increase

  1. In case of each GO term where statistically significant changes were observed in network parameters in HIV-1 treated cells at 12 h time-point the GO identifier, the changed parameter and the direction of change is indicated