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Fig. 2 | BMC Bioinformatics

Fig. 2

From: IRESpy: an XGBoost model for prediction of internal ribosome entry sites

Fig. 2

QMFE calculation examples of IRES and non-IRES sequences. a PMFE of randomized sequences (density plot) and PMFE of the CrPV IGR IRES (viral IRES, PMFE = -47.5, QMFE = 0.001), the ERH 5′ UTR (housekeeping gene, PMFE = -12.7, QMFE = 0.99), Apaf-1 cellular IRES (PMFE = -76, QMFE = 0.66), and CrPV non-IRES regions (position: 6200–6399, PMFE = -22.2, QMFE = 0.94). b QMFE of 200 base segments across the whole genomic CrPV mRNA. The QMFE shows minimal values in the regions of the known the 5’UTR IRES (bases 1–708) and IGR IRES (bases 6000–6200)

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