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Table 1 MBD Pulldown scale factors

From: A model of pulldown alignments from SssI-treated DNA improves DNA methylation prediction

n mCpGs

0

1

2

3

4

5

6

≥7

C n

1

1.489

5.468

32.31

124.7

207.3

233.2

259.7

% s ss

-

1.7%

2.3%

2.2%

3.3%

4.8%

19%

81%

  1. These scale factors are ratios of pulldown efficiencies comparing the SssI Control and Input Control libraries, and represent the probability that a fragment with n mCpGs will be pulled-down, sequenced, and aligned relative to a fragment with 0 mCpGs. A sample-to-sample standard deviation, sss, was calculated by sub-sampling by chromosome, and is given as a percentage of the Cn value
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BMC Bioinformatics

ISSN: 1471-2105

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