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Table 1 MBD Pulldown scale factors

From: A model of pulldown alignments from SssI-treated DNA improves DNA methylation prediction

n mCpGs 0 1 2 3 4 5 6 ≥7
C n 1 1.489 5.468 32.31 124.7 207.3 233.2 259.7
% s ss - 1.7% 2.3% 2.2% 3.3% 4.8% 19% 81%
  1. These scale factors are ratios of pulldown efficiencies comparing the SssI Control and Input Control libraries, and represent the probability that a fragment with n mCpGs will be pulled-down, sequenced, and aligned relative to a fragment with 0 mCpGs. A sample-to-sample standard deviation, sss, was calculated by sub-sampling by chromosome, and is given as a percentage of the Cn value