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Fig. 2 | BMC Bioinformatics

Fig. 2

From: A purely bioinformatic pipeline for the prediction of mammalian odorant receptor gene enhancers

Fig. 2

Olfactory receptor loci according to different cutoff intergenic distances. a Line chart reporting number of clusters (magenta) and solitary genes (green) of the mouse main olfactory epithelium (MOE) list, for threshold distances between 0.1 and 100 Mb (threshold increment = 0.1 Mb). The shadowed box (magnified on the right) details on cluster (magenta) and solitary gene (green) number for threshold values equal to 0.1, 0.2, 0.5 and 1 Mb. b Bar charts for architectures derived from the four aforementioned cutoff distances. Each couple of columns refers to a cluster: magenta bars indicate the number of MOE genes found in it, whereas gray bars report the average distance between its pairs of neighboring members. Clusters are numbered according to chromosomal location, but are presented (left to right) from the richest (in terms of number of genes) to miniclusters (i.e. systems made up by two genes). Bar charts do not display solitary genes. c Chromosome charts mapping clusters (magenta intervals) and solitary genes (green squares) for the mouse MOE 0.5 (left graph) and 1 Mb (right graph) threshold. The latter is one of those lists utilized to search for elements (we indicated that by enclosing its title line in an orange box). Predicted enhancers are depicted as orange triangles. While elements are invariably presented as located on genomic plus (+) strand, solitary genes are annotated on their sense strand (be it plus or minus, −). A location containing three predicted elements close to each other is magnified (black shadowed box). Chromosome bands represent Giemsa staining

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