Skip to main content
Fig. 6 | BMC Bioinformatics

Fig. 6

From: A multiscale mathematical model of cell dynamics during neurogenesis in the mouse cerebral cortex

Fig. 6

Comparison of wild-type (WT, in blue) and Ftm−/− (KO, in red) results. Coefficients and outputs of the model for the parameter sets #3 and #4 in Table 4, superimposed on experimental values represented by their mean and global range. Panel a displays IPPgenic division rate of APs, γ(t). Panel b displays the input flux of AP cells, FAP(t), the + signs show the location of the inflexion times t and t+. Panel c displays the cumulative number of AP cells entering neurogenesis, \(\int _{0}^{t}F_{AP}(\tau)d\tau \). Panel d displays \(\overline {IP}(t)\) computed by the model (7). Panel e displays the IPP number curve \(\overline {IPP}(t)\) computed by the model (6). Panel f displays the neuron number curve N(t) computed by the model (8). The blue (respectively red) dots and vertical bars correspond to the mean values and whole range of the control (resp. mutant) experimental dataset. The ratio \(r^{N}_{AP}=2.73\) for the control and \(r^{N}_{AP}=2.65\) for the mutant

Back to article page