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Table 1 Comparison of different software

From: RetSynth: determining all optimal and sub-optimal synthetic pathways that facilitate synthesis of target compounds in chassis organisms

Software

Easily available

Optimal pathways

Sub-optimal pathways

Chemical optimal/suboptimal pathways

Flux balance analysis

Graphical user interface

Enzyme promiscuity

RetSynth

√

√

√

√

√

√

 

OptStrain

 

√

√

 

√

  

GEM-Path

 

√

    

√

MetaRoute

√

√

   

√

 

RouteSearch

√

√

√

  

√

 

Retrobiosynthesis

 

√

     

RetroPath

√

√

√

  

√

√

  1. Depicts the different features of each software