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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Proper evaluation of chemical cross-linking-based spatial restraints improves the precision of modeling homo-oligomeric protein complexes

Fig. 2

Comparison of using SASDs over EUCs to reduce the Intra- vs. Inter-subunit ambiguity based on the inter-residue distance. a A heatmap showing a redistribution of assignations when using SASDs over EUCs. Values represent the proportion of individual assignations. The total values obtained with each method are shown in header row and column, while the body of the heatmap shows the proportions of combinations. Values in parentheses represent the relative proportion of assignations obtained using SASDs, excluding Non-accessible. b Comparison of redistribution of assignations between different EUC thresholds (red bars) and using SASDs over EUCs (blue bars). Values inside bar sections represent the relative population of individual assignations. c Distribution of differences between Inter- and Intra-subunit distances. Median values were calculated from kernel density estimates [20]. d Distribution of differences between calculated SASDs and EUCs. Median values were calculated from kernel density estimates [20]

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