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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Proper evaluation of chemical cross-linking-based spatial restraints improves the precision of modeling homo-oligomeric protein complexes

Fig. 3

Evaluation of the effect of addressing cross-links as ambiguous (Oblivious vs. Normal) and oriented (oriented vs. stringent) on docking precision. a Comparison of precision of Oblivious-oriented, Oblivious-stringent, Normal-oriented, and Normal-stringent scoring functions. b Comparison of average precision when using SASDs over EUCS for all evaluated scoring functions. Results obtained with SASDs are presented as dotted bars. Values represent the mean precision of all structures in the dataset with SEM. Quade ranking test, followed by Quade’s post-hoc test for unreplicated blocked data with Bonferroni correction * p-values < 0.05, ** 0.01, *** 0.001, **** 0.0001

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