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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Predicting the artificial immunity induced by RUTI® vaccine against tuberculosis using universal immune system simulator (UISS)

Fig. 1

The pulmonary tuberculosis – immune system interaction disease model. Conceptual description of the main entities and interactions of MTB – immune system. The main two compartments are represented: the lung and the peripheral lymph nodes. The representation depicts both cellular and humoral response when MTB droplets infect alveolar macrophages resident in the lung. The cascade of cytokines and chemokines is also represented with possible different behaviors depending on the virulence of the MTB strain

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