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Table 1 The pseudocode for conducting DC gene search on the network

From: DNLC: differential network local consistency analysis

Input: G (gene network), M (expression matrix), y (clinical outcome vector), T (local fdr threshold), C (confounder matrix)
Output: Collection of DC genes: S
Standardize each row of M
Local Moran’s I Matrix I = Local _ Moran _ I(G, M)
For each node i in  G do
ti = t statistic from generalized linear model y~Ii + C
End for
Fit {ti}i = 1, …, p to mixture model using local fdr to find {lfdri}i = 1, …, p
S = {i : lfdri ≤ T}
Return S