Table 1 HLA I binding profiles of conserved and experimentally verified HCMV-specific CTL epitopes
From: Computational assembly of a human Cytomegalovirus vaccine upon experimental epitope legacy
Epitope | Antigen gene | Antigen accession | a HLA I restriction | b Extended HLA I restriction | c PPC (%) |
|---|---|---|---|---|---|
QYDPVAALF | UL83 | Q6SW59 | A*24:02, A*01:01, C*04:01 | A*:01:01, A*24:02, B*15:16, B*38:01, B*39011, B*3909, B*5801, C*04:01, C*07:02 | 66.71 |
NLVPMVATV | UL83 | Q6SW59 | A*02:01, A*02:02, A*02:03, A*02:06, A*02:11, A*02:12, A*02:16, A*02:19, A*24:02, A*69:01, A*03, B*07:02 | A*02:01, A*02:02, A*02:03, A*02:05, A*02:06, A*02:09, A*02:14, A*68:02, A*02:12, A*02:16, A*02:19, A*02:11, A*69:01, A*24:02, B*07:02 | 58.98 |
TTVYPPSSTAK | UL32 | Q6SW99 | A*03:01 | A*0301, B*15:02, B*15:08, C*07:02 | 34.47 |
HERNGFTVL | UL83 | Q6SW59 | B*40:01, B*40:02, B*60 | A*2902, B*0702, B*1510, B*40:01, B*40:02 | 24.21 |
TPRVTGGGAM | UL83 | Q6SW59 | A*02:01, B*07:02 | A*02:01, B*07:02, B*55:02, B*27:06 | 9.79 |
CEDVPSGKL | UL83 | Q6SW59 | B*40:01, A*03, B*60 | B*38:01, B*40:01 | 2.78 |
QTVTSTPVQGR | UL32 | Q6SW99 | A*68:01 | A*33:01, A*68:01 | 1.12 |
AELEGVWQPA | UL83 | Q6SW59 | B*40:06 | A*02:09, B*40:06 | 0 |