Skip to main content

Table 5 Epitope ensemble vaccine for HCMV

From: Computational assembly of a human Cytomegalovirus vaccine upon experimental epitope legacy

EpitopeAntigen geneAntigen accessionBLAST hit human (%)BLAST hit HMP (%)PPC (%)
CD8 T cell epitope vaccine component
 QYDPVAALFUL83Q6SW59NP_060360.3 (66.67)ETS98202.1 (78.00)66.71
 NLVPMVATVUL83Q6SW59AMD82163.1 (66.67)KWZ77571.1 (78.00)58.98
 TTVYPPSSTAKUL32Q6SW99CAC15059.1 (63.64)OFS88048.1 (72.73)34.47
 HERNGFTVLUL83Q6SW59XP_016879611.1 (77.78)EGG81521.1 (77.78)24.21
 TPRVTGGGAMUL83Q6SW59AGP01160.1 (70.00)EJD64485.1 (80.00)9.79
 QTVTSTPVQGRUL32Q6SW99NP_005892.1 (63.64)EHY57399.1 (82.00)1.12
CD4 T cell epitope vaccine component
 SIYVYALPLKMLNIPUL83Q6SW59XP_006724177.2 (46.67)AEA20835.1 (73.33)63.95
 KLFMHVTLGSDVEEDLTMTRUL83Q6SW59EAX02867.1 (45.00)ERJ00718.1 (45.00)48.03
 YQEFFWDANDIYRIFUL83Q6SW59EAW98902.1 (46.67)EIJ68880.1 (60.00)27.69
 LPLKMLNIPSINVHHUL83Q6SW59EAX02055.1 (46.67)EEU31012.1 (73.33)21.87
 CSMENTRATKMQVIGUL83Q6SW59EAW54200.1 (53.33)EGL44246.1 (73.33)37.99
 AGILARNLVPMVATVUL83Q6SW59BAC11142.1 (46.67)EFV13316.1 (73.33)11.53
B cell epitope vaccine component
 AFHLLLNTYGRUL75Q6SW67EAW77317.1 (63.64)KXA44279.1 (63.64) 
 *TYNSSLRNSUL75Q6SW67AHA56189.1 (78.00)EFE23794.1 (90.00)
 *TPEAANSVLLDUL115F5HCH8NP_001017403.1 (72.73)OFU98142.1 (72.73)
  1. We show closest blast hits to human Proteins and Human Microbiome Proteins. The B cell epitope component contains one epitope validated experimentally and 2 predicted epitopes (*). PPC of the entire CD8 and CD4 T cell component is 97.41 and 92.49%