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Fig. 5 | BMC Bioinformatics

Fig. 5

From: HTRgene: a computational method to perform the integrated analysis of multiple heterogeneous time-series data: case analysis of cold and heat stress response signaling genes in Arabidopsis

Fig. 5

TF network analysis. The TF network analysis produced seven and four clusters for cold (a) and heat (b) stress, respectively. In the TF network clusters, hub regulator TFs that regulate over the target five genes (TG) of these clusters were observed, which are C1 (AGL, CDF5), C2 (ERF2, ERF4, ERF5, ERF6), C3 (CBF1, CBF2, CBF3), C4(STZ), C5(ABF1, RVE6), C6(DREB2B), and C7(WRKY33, WRKY40) for cold stress and C1(HSFB2A), C2(HSFB2B), C3(BZIP28), and C4(AT4G28140) for heat stress. The rhombus nodes represent TFs, and rectangular nodes represent TGs. The blue nodes represent early phase cluster genes and grey nodes late phase cluster genes. It shows that the hub regulator TFs of early half phase clusters regulate the TGs of late half phase clusters

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