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Fig. 8 | BMC Bioinformatics

Fig. 8

From: Integrating protein localization with automated signaling pathway reconstruction

Fig. 8

PLNet2: LocPL pathway reconstructions (first 100 paths). a IL2 pathway reconstructions before applying the dynamic program (left) compared to after applying the dynamic program (right). b Topologies of other pathway reconstructions; larger figures provided in Additional file 1: Figures S3, S4 and S5. Receptors are labeled as triangles, transcriptional regulators are rectangles, intermediary proteins are ellipses. Color denotes compartment localization; proteins may belong to multiple compartments (and will be lighter shades). Networks were generated using GraphSpace [39], and are available at http://graphspace.org/graphs/?query=tags:LocPL

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