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Table 1 Comparison of MIENTURNET with other web tools developed for the identification and analysis of miRNA-target interactions (MTIs)

From: MIENTURNET: an interactive web tool for microRNA-target enrichment and network-based analysis

Tools miTEA GSEA/MSigDB miEAA miRNet miRTargetLink MIENTURNET
Reference [12] [13] [14] [15] [16]  
Last Release February 2013 July 2018 April 2016 March 2018 April 2016 March 2019
Input list       
Gene identifiers Gene symbol, RefSeq, Uniprot, Unigene, Ensembl Gene symbol, Entrez - Gene symbol, Ensembl, Entrez Gene symbol Gene symbol
miRNA identifiers - - ID ID, Accession ID ID
Others - - - - -
Queries       
Multiple item
Organisms       
Species Human, Mouse, Rat, Zebrafish, Fruit fly Human Human Human, Mouse, Rat, Cattle, Chicken, Zebrafish, Fruit fly, Worm, Helminth Human Human, Mouse, Rat, Zebrafish, Fruit fly, Worm
Species # 5 1 1 9 1 6
Reference database       
Predicted target genes TargetScan, MicroCosm, EIMMo MSigDB - miRanda miRanda TargetScan
Experimental target genes - - miRTarBase TarBase, miRTarBase, miRecords miRTarBase, in-house data miRTarBase
Others - - - -
Statistical analysis       
Differential expression - - - - -
Functional enrichment -
miRNA-target enrichment - -
MTI network       
Visualization - - -
Customization - - -
Filtering - - -
MTI network analysis       
Degree - - - -
Betweenness - - - -
Closeness - - - - -
Average shortest path - - - - -
Eccentricity - - - - -
Clustering coefficient - - - - -
Fit power low - - - - -
  1. *miRNA identifiers from miRBase database [28]
  2. **species common name (scientific name): Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Cattle (Bos taurus), Chicken (Gallus gallus), Zebrafish (Danio rerio), Fruit fly (Drosophila melanogaster), Worm (Caenorhabditis elegans), Helminth (Schistosoma mansoni)
  3. ***only for Cattle, Chicken, Helminth