Table 1 GO TERMS ENRICHED IN WHOLE BLOOD and related disease genes
From: TS-GOEA: a web tool for tissue-specific gene set enrichment analysis based on gene ontology
GO term | GO function | Disease-related gene |
|---|---|---|
GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | GATA1,HOXD13CEBPA,FLI1,NR4A3,CEBPA |
GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | FLI1,CEBPA,GATA1,GATA2,HOXD13,NR4A3 |
GO:0000987 | proximal promoter sequence-specific DNA binding | CEBPA,GATA1,HOXD13,NR4A3 |
GO:0001077 | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | GATA1,GATA2,HOXD13,CEBPA,FLI1,NR4A3,CEBPA |
GO:0001158 | enhancer sequence-specific DNA binding | GATA1,GATA2,HOXD13 |
GO:0002020 | protease binding | VWF,ITGB,ELANE,NR4A3 |
GO:0003700 | obsolete negative regulation of diuresis | GATA1,GATA2,HOXD13,CEBPA,FLI1,CEBPA |
GO:0004872 | receptor activity | TBXA2R,CD36,F2,GP1BB,MPL,NR4A3 |
GO:0070892 | lipoteichoic acid receptor activity | CD36 |
GO:1990837 | sequence-specific double-stranded DNA binding | CEBPA,GATA1,GATA2,HOXD13,NR4A3 |