Table 1 Statistics for evaluating disease-related metabolite network
From: Prioritizing candidate diseases-related metabolites based on literature and functional similarity
Disease name | Disease Ontology | Test node | Positive group | Version 2017 | Version 2018 |
|---|---|---|---|---|---|
L-2-hydroxyglutaric aciduria | DOID:0050574 | 2 | 4 | 2 | 4 |
medium chain acyl-CoA dehydrogenase deficiency | DOID:0080153 | 1 | 16 | 15 | 16 |
short chain acyl-CoA dehydrogenase deficiency | DOID:0080154 | 1 | 4 | 3 | 4 |
Crohn’s colitis | DOID:0060192 | 5 | 8 | 3 | 16 |
cerebrotendinous xanthomatosis | DOID:4810 | 5 | 7 | 2 | 9 |
maple syrup urine disease | DOID:9269 | 6 | 23 | 17 | 24 |
abetalipoproteinemia | DOID:1386 | 3 | 4 | 1 | 4 |
celiac disease | DOID:10608 | 11 | 22 | 11 | 82 |
methylmalonic acidemia | DOID:14749 | 1 | 2 | 1 | 2 |
irritable bowel syndrome | DOID:9778 | 5 | 7 | 2 | 15 |
Fanconi syndrome | DOID:1062 | 1 | 2 | 1 | 5 |
citrullinemia | DOID:9273 | 6 | 8 | 2 | 8 |
inflammatory bowel disease 1 | DOID:0110892 | 5 | 8 | 3 | 16 |
isovaleric acidemia | DOID:14753 | 2 | 11 | 9 | 12 |
type 2 diabetes mellitus | DOID:9352 | 1 | 27 | 27 | 27 |
aromatic L-amino acid decarboxylase deficiency | DOID:0090123 | 2 | 9 | 7 | 12 |
cholesterol ester storage disease | DOID:14502 | 1 | 2 | 1 | 2 |
congenital adrenal hyperplasia | DOID:0050811 | 15 | 18 | 3 | 28 |
Crohn’s disease | DOID:8778 | 5 | 8 | 3 | 16 |