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Table 2 Mean TC and SP Scores for 14 Aligners on BAliBASE

From: ProbPFP: a multiple sequence alignment algorithm combining hidden Markov model optimized by particle swarm optimization with partition function

Aligner

Mean TC score

Mean SP score

ProbPFP

*67.03*

*82.50*

Probalign

67.27

82.53

ProbCons

65.22

81.55

T-Coffee

64.93

80.82

PicXAA

66.08

81.33

CONTRAlign

58.10

77.59

COBALT

57.49

76.08

Clustal Ω

59.38

75.96

MUSCLE

58.27

75.60

KALIGN

59.66

76.99

MAFFT

52.58

72.46

ClustalW

49.21

69.63

Align-m

56.04

71.45

DIALIGN

48.22

68.63

  1. The scores in this table are multiplied by 100. In each column, the maximum score is highlighted in bold, while the second highest score is displayed between two asterisks