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Table 3 Mean TC and SP Scores for 14 Aligners on SABmark

From: ProbPFP: a multiple sequence alignment algorithm combining hidden Markov model optimized by particle swarm optimization with partition function

Aligner

Mean TC score

Mean SP score

ProbPFP

39.56

59.84

Probalign

38.63

59.53

ProbCons

39.17

*59.69*

T-Coffee

*39.53*

59.14

PicXAA

39.11

59.37

CONTRAlign

35.59

57.54

COBALT

36.00

56.71

Clustal Ω

35.47

55.02

MUSCLE

33.47

54.51

KALIGN

33.22

52.13

MAFFT

32.57

52.63

ClustalW

31.37

51.92

Align-m

31.07

46.19

DIALIGN

27.11

47.09

  1. The scores in this table are multiplied by 100. In each column, the maximum score is highlighted in bold, while the second highest score is displayed between two asterisks