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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Domainoid: domain-oriented orthology inference

Fig. 2

Example of a common scenario for discordant orthologies discovered by Domainoid, where the primary protein has more than two secondary proteins. The YjeF_N and Carb_kinase domains are both involved in NAD(P) H dehydration, where the former domain performs epimerization. The two domains have different evolutionary histories, causing discordant domain orthology as revealed by Domainoid. Identifiers are UniProt accessions and Pfam domains (shown as coloured boxes) respectively

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BMC Bioinformatics

ISSN: 1471-2105

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