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Table 1 Study of contralateral breast cancers

From: An EM algorithm to improve the estimation of the probability of clonal relatedness of pairs of tumors in cancer patients

Case #

Somatic mutations

Details of matches

 

Left breast

Right breast

Matches

Mutations

Probabilities

1

9

7

0

  

2

3

3

0

  

3

2

7

0

  

4

8

10

0

  

6

6

5

0

  

8

6

2

1

ARID1A E250fs

< 1/1000

9

2

3

0

  

12

14

3

0

  

13

3

3

0

  

15

8

5

0

  

16

10

8

0

  

17

6

8

0

  

18

8

2

0

  

21

4

3

0

  

23

10

4

0

  

24

4

3

0

  

25

4

6

0

  

26

6

5

0

  

27

4

5

0

  

29

3

1

0

  

30

6

5

0

  

31

6

5

0

  

32

5

4

0

  

33

6

4

0

  

35

5

4

0

  

36

3

4

3

CDH1 S111fs

< 1/1000

    

TBX3 T267fs

< 1/1000

    

EPPK1 R2337H

< 1/1000

38

8

2

0

  

40

10

1

0

  

41

0

9

0

  

43

4

4

0

  

44

9

21

0

  

45

3

4

0

  

48

2

3

2

MLH3 M346R

< 1/1000

    

MAP3K1 R248*

< 1/1000

52

5

7

0

  

56

2

5

0

  

58

3

4

0

  

59

2

3

0

  

62

4

4

0

  

63

3

9

1

PIK3CA H1047R

0.137

64

5

4

0

  

66

33

3

0

  

67

4

1

1

PIK3CA H1047R

0.137

70

5

2

0

  

71

3

1

0

  

72

1

3

0

  

74

2

1

0

  

75

4

3

1

PIK3CA H1047R

0.137

76

7

5

0

  

77

3

1

0

  
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BMC Bioinformatics

ISSN: 1471-2105

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