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Table 6 The final selected genes from the gene selection method DGS

From: Deep gene selection method to select genes from microarray datasets for cancer classification

Gene symbol

Gene Name

Chr.

NCBI UniGene number

Specification

LCK

lymphocyte-specific protein tyrosine kinase

1

3932

The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells

DUSP6

dual-specificity phosphatase6

12

1848

This gene inactivates (ERK2), resulting in tumor suppression and apoptosis. The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily

ERBB3

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

12

2065

Also known as HER3 (human epidermal growth factor receptor 3) This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases which are often aberrantly expressed and/or activated in human cancers

MMD

monocyte-to-macrophage differentiation associated protein

17

23,531

This protein is expressed in mature macrophages but the function of this protein is still unknown.

  1. Note: NCBI UniGene number with more information about the genes can be found from NCBI website https://www.ncbi.nlm.nih.gov/geo/