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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Predictive modelling using pathway scores: robustness and significance of pathway collections

Fig. 1

Workflow designed to produce a pathway space representation of a gene expression data set. The expression values for all qi genes in the i’th pathway (green columns) are extracted from the original (nxm) expression matrix to form a new (nxqi) matrix. PCA is performed on this matrix and the score on the first component retained as the pathway score. This is repeated for each of the k pathways and the pathway scores assembled into a new ‘pathway space’ matrix of dimension (nxk) (orange)

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