The assessment of efficient representation of drug features using deep learning for drug repositioning

BMC Bioinformatics

Table 4 New drug-disease associations score obtained by our pipeline

Drug name	Disease name	MONDO	Drug-Bank ID	Score	Reference
Asthma	Budesonide	0004979	DB01222	0.962	https://ClinicalTrials.gov/show/NCT03034005
Addison Disease	Dexamethasone	0009410	DB01234	0.938	https://ClinicalTrials.gov/show/NCT03210545
Lupus Nephritis	Mycophenolate Mofetil	0005556	DB00688	0.936	https://ClinicalTrials.gov/show/NCT03920059
Cancer	Dexamethasone	0004992	DB01234	0.931	https://ClinicalTrials.gov/show/NCT02815319
Hypothyroidism	Levothyroxine	0005420	DB00451	0.913	https://ClinicalTrials.gov/show/NCT02577367
Paroxysmal Nocturnal Hemoglobinuria	sirolimus	0018641	DB00877	0.876	https://ClinicalTrials.gov/show/NCT03866681
Multiple Sclerosis	Fingolimod	0005301	DB08868	0.843	https://ClinicalTrials.gov/show/NCT02232061
Peripheral Arterial Disease	Ramipril	0005386	DB00178	0.843	https://ClinicalTrials.gov/show/NCT02842424
Chronic Hepatitis b	Tenofovir Alafenamide	0005366	DB09299	0.827	https://ClinicalTrials.gov/show/NCT03753074
Kidney Disease	Dexmedetomidine	0005240	DB00633	0.825	https://ClinicalTrials.gov/show/NCT02707809
Multiple Sclerosis	Cladribine	0005301	DB00242	0.821	https://ClinicalTrials.gov/show/NCT03961204
Asthma	N-acetylcysteine	0004979	DB06151	0.809	https://ClinicalTrials.gov/show/NCT03581084
Peutz-Jeghers Syndrome	Rapamycin	0008280	DB00877	0.807	https://ClinicalTrials.gov/show/NCT03781050
Malaria	primaquine	0005136	DB01087	0.799	https://ClinicalTrials.gov/show/NCT03916003
Alopecia Areata	Tofacitinib	0005340	DB08895	0.777	https://ClinicalTrials.gov/show/NCT03800979
Multiple Sclerosis	Fampridine	0005301	DB06637	0.766	https://ClinicalTrials.gov/show/NCT02849782

ISSN: 1471-2105