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Table 2 Comparison of Independent Approximation and Exact Calculations.

From: SCOPIT: sample size calculations for single-cell sequencing experiments

Subpopulation frequency# of subpopulationsCells required (exact)Cells required (approx.)
0.16186186
0.238585
0.325353
0.18191191
0.248787
0.423939
0.19193193
0.335555
0.110195194
0.258989
0.523030
  1. The number of cells required to achieve a 95% certainty of sampling sufficiently many cells from each subpopulation. The number of cells was calculated in two ways: by an exact calculation, and by an approximate calculation in which the counts of different subpopulations were assumed to be independent