From: Recommendations for performance optimizations when using GATK3.8 and GATK4
Async I/O activated?
Tool Name
no
all
only for samtools I/O
BaseRecalibrator
4.07
2.95
2.88
ApplyBQSR
2.38
2.07
2.08
HaplotypeCaller
17.25
17.31
17.08