Fig. 7

Distances between E.coli strains B4Sb227 and BW2952, estimated by Read-SpaM and Mash using simulated reads from one genome and the assembled second genome (top) and simulated reads from both genomes (bottom) for different levels of sequencing coverage. Horizontal lines are reference distances, estimated by FSWM from the assembled full genomes and using fragmented genomes (see main text)