Fig. 3

scDC on simulated dataset. scDC has been applied to four simulated datasets. a Each dot represents a pair of values containing the mean proportion estimate calculated from scDC (x-axis) and the true proportion from the simulation data (y-axis). Across all four datasets, all dots lie on the diagonal line, even when the proportion of a cell-type is as low as 5%. This demonstrates that scDC is highly accurate in estimating cell-type composition. b Each simulated dataset contains two conditions, represented suing colours red and blue. The bar chart shows proportion estimates of each cell-type n1 to n4 for each subject in the dataset. The horizontal black line represents the BCa confidence interval associated with the proportion estimate