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Fig. 8 | BMC Bioinformatics

Fig. 8

From: Transcription factor regulatory modules provide the molecular mechanisms for functional redundancy observed among transcription factors in yeast

Fig. 8

The Ste12 regulatory module is experimentally verified in yeast pheromone response and filamentation. Ste12, Mcm1 and Tec1 are together suggested by the proposed method to form a TF regulatory module. Several studies proved that when the cell is stimulated with mating pheromone, Ste12 undergoes phosphorylation to recognize the PREs in mating genes with Mcm1 and Tec1 is degraded by the proteasome machinery. And it has been verified that when filamentation signals are sensed, Tec1 tethers Ste12 to activate filamentation genes

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BMC Bioinformatics

ISSN: 1471-2105

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