Table 1 The module-inferred functional binding target gene sets have equal or better biological significance than pure knockout-inferred direct regulatory targets

128 (70.3%) TFs showed equal or better log enrichment scores

in module-inferred functional binding target genes while only

54 (29.7%) TFs showed higher log enrichment scores in the

direct regulatory data.

109 (59.9%) TFs showed equal or better log enrichment scores

in module-inferred functional binding target genes while only

73 (40.1%) TFs showed higher log enrichment scores in the

direct regulatory data.

150 (82.4%) TFs showed equal or better log enrichment scores

in module-inferred functional binding target genes while only

34 (18.7%) TFs showed higher log enrichment scores in the

direct regulatory data.

68 (37.4%) of the module-inferred functional binding gene

sets reveled prevalence of protein interaction while only

13 (7.1%) direct regulatory gene sets did.

Module-inferred functional binding genes had higher

expression coherence in 32 different conditions while in no

condition the direct regulatory data got higher expression

coherence.