Skip to main content

Table 1 A portion of enriched or depleted biological processes, pathways and diseases associated with breast cancer by using miRNA enrichment analysis

From: Identifying miRNA synergism using multiple-intervention causal inference

Category

Subcategory

Enrichment

p-value

#miRNAs

Gene Ontology

GO0007050:cell cycle arrest

enriched

3.079E-02

27

GO0007093:mitotic cell cycle checkpoint

enriched

8.732E-03

10

GO0051781:positive regulation of cell division

enriched

1.146E-02

16

GO0002903:negative regulation of b cell apoptotic process

depleted

3.023E-02

3

GO0042981:regulation of apoptotic process

enriched

2.025E-02

21

GO0043065:positive regulation of apoptotic process

enriched

7.562E-03

27

GO0030334:regulation of cell migration

enriched

3.296E-02

14

GO0010595:positive regulation of endothelial cell migration

enriched

2.851E-02

12

GO0030335:positive regulation of cell migration

enriched

2.327E-02

20

GO0045595:regulation of cell differentiation

enriched

3.939E-02

10

GO0045446:endothelial cell differentiation

depleted

3.330E-04

2

GO0050678:regulation of epithelial cell proliferation

enriched

3.845E-02

3

GO0072091:regulation of stem cell proliferation

enriched

3.497E-02

2

GO0010719:negative regulation of epithelial to mesenchymal transition

depleted

4.996E-02

3

Pathways

hsa04210:Apoptosis

enriched

3.859E-02

22

P00038:JAK STAT signaling pathway

enriched

4.995E-03

2

P00056:VEGF signaling pathway

enriched

3.376E-02

15

WP304:Kit receptor signaling pathway

enriched

7.517E-03

18

Diseases

Breast Neoplasms

enriched

7.184E-03

11